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Senior Staff Bioinformatics Scientist

Illumina, Inc.
hybridUSD 170,600 - 255,800 / year
US - California - San Diego; US - Remote Posted Aug 11, 2026

About this role

Senior Staff Bioinformatics Scientist

Responsibilities

  • Lead development of novel algorithms and analytical methods for RNA and multiomic sequencing applications.
  • Design, evaluate, and implement scalable bioinformatics workflows for bulk RNA-seq, single-cell sequencing, CRISPR/Perturb-seq analysis, ATAC-seq, CROP-seq, and emerging multiomic assays.
  • Apply machine learning, AI-based methods, foundation models, LLM-enabled workflows, and biological foundation models to accelerate method development, validation, interpretation, and product innovation.
  • Develop production-quality software solutions in collaboration with bioinformatics scientists, software engineers, FPGA engineers, assay development teams, and product teams.
  • Lead technical projects, define requirements, influence product direction, evaluate risks, and drive innovation across multiple product cycles.

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